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Vibratory urticaria

DOID EFO MESH SNOMED PheWeb

L12_URTICA_VIBR

vibratory urticaria: This very rare form of angioedema develops in reply to contact with vibration. In vibratory angioedema, symptoms develop within two to five minutes after contact with vibration and dissolve after about an hour. Patients with this disorder do not suffer from dermographism or pressure urticaria. Vibratory angioedema is diagnosed by holding a vibrating device such as a laboratory vortex machine against the forearm for four minutes. Speedy swelling of the whole forearm extending into the upper arm is also noted later. The principal treatment is avoidance of vibratory stimulants. Antihistamines have also been proven helpful.[

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L50.4
Hospital discharge: ICD-9 7084
Cause of death: ICD-10 L50.4
Cause of death: ICD-9 7084

2 out of 7 registries used, show all original rules.

19

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Check minimum number of events None

19

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Include endpoints None

19

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Remove individuals based on genotype QC

19

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L12_URTICA_VIBR

Control definitions

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L50
Name in latin Urticaria ex vibratione

Not enough data for upset plot.

Or the full data table

Summary Statistics

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Key figures

All Female Male
Number of individuals 19 12 7
Unadjusted prevalence (%) 0.01 0.01 0.00
Mean age at first event (years) 46.40 42.36 53.34

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICA_VIBR – Vibratory urticaria
GWS hits:

Survival analyses between endpoints

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Plot

before Vibratory urticaria
after Vibratory urticaria

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Drugs most likely to be purchased after Vibratory urticaria

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Endpoint not on priority list, no data to show.