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Speech and linguistic disorders

KRA_PSY_SPEELING

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F80, F81
Hospital discharge: ICD-9 315[0-3]|3159
Hospital discharge: ICD-8 31610
Cause of death: ICD-10 F80, F81
Cause of death: ICD-9 315[0-3]|3159
Cause of death: ICD-8 31610

2 out of 7 registries used, show all original rules.

2745

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Check minimum number of events None

2745

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Include endpoints None

2745

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Remove individuals based on genotype QC

2571

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KRA_PSY_SPEELING

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2571 1266 1305
Unadjusted prevalence (%) 0.68 0.60 0.78
Mean age at first event (years) 21.82 24.39 19.33

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: KRA_PSY_SPEELING – Speech and linguistic disorders
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Speech and linguistic disorders

Endpoint not on priority list, no data to show.