Specific development disorders of speech and language

F5_SPEECH

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F80
Hospital discharge: ICD-9 3153
Hospital discharge: ICD-8 3060
Cause of death: ICD-10 F80
Cause of death: ICD-9 3153
Cause of death: ICD-8 3060

2 out of 7 registries used, show all original rules.

1765

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Check minimum number of events None

1765

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Include endpoints

1765

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Remove individuals based on genotype QC

1648

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F5_SPEECH

Control definitions

Control exclude F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 F80-F89
Name in latin Perturbationes specificae progressus dictionis et linguae

Summary Statistics

Key figures

All Female Male
Number of individuals 1648 766 882
Unadjusted prevalence (%) 0.44 0.36 0.53
Mean age at first event (years) 22.99 26.92 19.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.02 [2.23, 11.30] 9.7e-5 64
15 years 0.01 1.14 [0.51, 2.55] 7.5e-1 10
5 years 0.01 4.61 [2.50, 8.51] 1.0e-6 21
1 year 0.00 18.16 [8.41, 39.23] 1.6e-13 26

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_SPEECH – Specific development disorders of speech and language
GWS hits:

Survival analyses between endpoints

Plot

before Specific development disorders of speech and language
after Specific development disorders of speech and language

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Drugs most likely to be purchased after Specific development disorders of speech and language

Endpoint not on priority list, no data to show.