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Ulcerative colitis (strict) with PSC

DOID EFO MESH SNOMED PheWeb

K11_UC_STRICT_PSC

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

K11_CHOLANGI_STRICT
and K11_UC_STRICT

213

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

213

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Remove individuals based on genotype QC

209

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K11_UC_STRICT_PSC

Control definitions

Control exclude K11_IBD, K11_CHOLANGI
Control conditions not K11_CHOLANGI_STRICT
and not K11_UC_STRICT

Extra metadata

First used in FinnGen datafreeze DF4

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 209 100 109
Unadjusted prevalence (%) 0.06 0.05 0.07
Mean age at first event (years) 30.23 30.33 30.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_UC_STRICT_PSC – Ulcerative colitis (strict) with PSC
GWS hits:

Survival analyses between endpoints

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Plot

before Ulcerative colitis (strict) with PSC
after Ulcerative colitis (strict) with PSC

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative colitis (strict) with PSC

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Endpoint not on priority list, no data to show.