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ILD related to systemic autoimmune disease

DOID EFO MESH SNOMED PheWeb

ILD_SYST_AUTO

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

ILD_ELSEWHERE

115

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

105

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Remove individuals based on genotype QC

104

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ILD_SYST_AUTO

Control definitions

Control exclude ILD_ENDPOINTS
Control conditions not ILD_ELSEWHERE

Extra metadata

First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 104 60 44
Unadjusted prevalence (%) 0.03 0.03 0.03
Mean age at first event (years) 56.89 54.27 60.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ILD_SYST_AUTO – ILD related to systemic autoimmune disease
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after ILD related to systemic autoimmune disease

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Endpoint not on priority list, no data to show.