≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Interstitial lung disease endpoints

DOID EFO MESH SNOMED PheWeb

ILD_ENDPOINTS

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

4337

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

4213

diagram downward connector
ILD_ENDPOINTS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

↥

List of similar endpoints to Interstitial lung disease endpoints based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 4213 1646 2567
Unadjusted prevalence (%) 1.12 0.78 1.54
Mean age at first event (years) 65.91 63.00 67.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.10 [5.70, 8.86] 1.3e-67 1153
15 years 0.01 2.24 [1.80, 2.80] 1.1e-12 320
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: ILD_ENDPOINTS – Interstitial lung disease endpoints
GWS hits: 13

Survival analyses between endpoints

↥

Plot

before Interstitial lung disease endpoints
after Interstitial lung disease endpoints

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Interstitial lung disease endpoints

↥

Endpoint not on priority list, no data to show.