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Hard cardiovascular diseases

DOID EFO MESH SNOMED PheWeb

I9_CVD_HARD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

63268

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Remove individuals based on genotype QC

61240

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I9_CVD_HARD

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF3

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 61240 20194 41046
Unadjusted prevalence (%) 16.24 9.58 24.69
Mean age at first event (years) 65.55 66.64 65.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.46 [4.11, 4.84] <1e-100 19948
15 years 0.01 2.50 [2.31, 2.72] <1e-100 7015
5 years 0.00 4.25 [3.95, 4.57] <1e-100 4182
1 year 0.01 33.31 [29.98, 37.01] <1e-100 6607

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CVD_HARD – Hard cardiovascular diseases
GWS hits: 54

Survival analyses between endpoints

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Plot

before Hard cardiovascular diseases
after Hard cardiovascular diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hard cardiovascular diseases

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Endpoint not on priority list, no data to show.