Calcific aortic valvular stenosis, operated

I9_CAVS_OPERATED

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

I9_CAVS_OPERATIONS1
or I9_CAVS_OPERATIONS2

9427

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

9153

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I9_CAVS_OPERATED

Control definitions

Control conditions not I9_CAVS_OPERATIONS1
or I9_CAVS_OPERATIONS2

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 9153 3415 5738
Unadjusted prevalence (%) 2.43 1.62 3.45
Mean age at first event (years) 70.93 72.16 70.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.95 [3.30, 4.74] 9.5e-50 2346
15 years 0.01 1.80 [1.55, 2.08] 3.6e-15 863
5 years 0.00 3.51 [3.09, 3.99] 2.6e-83 789
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CAVS_OPERATED – Calcific aortic valvular stenosis, operated
GWS hits: 22

Survival analyses between endpoints

Plot

before Calcific aortic valvular stenosis, operated
after Calcific aortic valvular stenosis, operated

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Drugs most likely to be purchased after Calcific aortic valvular stenosis, operated

Endpoint not on priority list, no data to show.