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Calcific aortic valvular stenosis, operated

PheWeb

I9_CAVS_OPERATED

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

I9_CAVS_OPERATIONS1
or I9_CAVS_OPERATIONS2

9427

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

9427

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Remove individuals based on genotype QC

9153

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I9_CAVS_OPERATED

Control definitions

Control conditions not I9_CAVS_OPERATIONS1
or I9_CAVS_OPERATIONS2

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 9153 3415 5738
Unadjusted prevalence (%) 2.43 1.62 3.45
Mean age at first event (years) 70.93 72.16 70.20

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.95 [3.30, 4.74] 9.5e-50 2346
15 years 0.01 1.80 [1.55, 2.08] 3.6e-15 863
5 years 0.00 3.51 [3.09, 3.99] 2.6e-83 789
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CAVS_OPERATED – Calcific aortic valvular stenosis, operated
GWS hits: 22

Survival analyses between endpoints

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Plot

before Calcific aortic valvular stenosis, operated
after Calcific aortic valvular stenosis, operated

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Calcific aortic valvular stenosis, operated

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Endpoint not on priority list, no data to show.