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Diseases of middle ear and mastoid

DOID EFO MESH SNOMED PheWeb

H8_MIDDLEMASTOID

suppurative otitis media: Inflammation of the middle ear with purulent discharge.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H65-H75
Cause of death: ICD-10 H65-H75

2 out of 7 registries used, show all original rules.

16284

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Check minimum number of events None

16284

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Include endpoints

25763

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Remove individuals based on genotype QC

24706

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H8_MIDDLEMASTOID

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of middle ear and mastoid based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 24706 14292 10414
Unadjusted prevalence (%) 6.55 6.78 6.26
Mean age at first event (years) 23.74 22.31 25.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.48 [1.16, 1.89] 1.4e-3 1230
15 years 0.01 1.03 [0.84, 1.26] 7.9e-1 544
5 years 0.00 1.41 [1.17, 1.71] 3.7e-4 217
1 year 0.00 3.85 [3.03, 4.88] 2.1e-28 108

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_MIDDLEMASTOID – Diseases of middle ear and mastoid
GWS hits: 10

Survival analyses between endpoints

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Plot

before Diseases of middle ear and mastoid
after Diseases of middle ear and mastoid

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of middle ear and mastoid

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Endpoint not on priority list, no data to show.