Disorders of vitreous body

H7_VITRBODYGLOBE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H43
Cause of death: ICD-10 H43

2 out of 7 registries used, show all original rules.

15507

diagram downward connector

Check minimum number of events None

15507

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

15177

diagram downward connector
H7_VITRBODYGLOBE

Control definitions

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H43-H45
Name in latin Morbositates corporis vitrei

Similar endpoints

List of similar endpoints to Disorders of vitreous body based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 15177 9581 5596
Unadjusted prevalence (%) 4.02 4.54 3.37
Mean age at first event (years) 62.12 61.32 63.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.44, 2.39] 1.6e-6 975
15 years 0.01 1.15 [0.91, 1.46] 2.3e-1 491
5 years 0.00 2.13 [1.76, 2.58] 1.4e-14 302
1 year 0.00 2.81 [2.14, 3.70] 1.6e-13 75

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_VITRBODYGLOBE – Disorders of vitreous body
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of vitreous body
after Disorders of vitreous body

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of vitreous body

Endpoint not on priority list, no data to show.