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Other and unspecified disorders of vitreous body

DOID EFO MESH SNOMED PheWeb

H7_VITROTH

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H43.8, H43.9
Hospital discharge: ICD-9 3792A
Hospital discharge: ICD-8 37840
Cause of death: ICD-10 H43.8, H43.9
Cause of death: ICD-9 3792A
Cause of death: ICD-8 37840

2 out of 7 registries used, show all original rules.

12344

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Check minimum number of events None

12344

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Include endpoints None

12344

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Remove individuals based on genotype QC

12004

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H7_VITROTH

Control definitions

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Summary Statistics

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Key figures

All Female Male
Number of individuals 12004 8039 3965
Unadjusted prevalence (%) 3.18 3.81 2.38
Mean age at first event (years) 63.26 62.30 65.21

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.75 [1.34, 2.30] 4.3e-5 536
15 years 0.01 1.10 [0.86, 1.41] 4.4e-1 279
5 years 0.00 1.75 [1.39, 2.22] 2.8e-6 156
1 year 0.00 2.41 [1.69, 3.43] 1.2e-6 40

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_VITROTH – Other and unspecified disorders of vitreous body
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified disorders of vitreous body
after Other and unspecified disorders of vitreous body

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified disorders of vitreous body

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Endpoint not on priority list, no data to show.