Retinal vein occlusion (central or branch)

DM_RET_VEIN_OCCLU

retinal vein occlusion: Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions

DIABETES_FG

71098

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H34.8

Cause of death: ICD-10 H34.8

2 out of 7 registries used, show all original rules.

803

Check minimum number of events None

803

Include endpoints None

803

Remove individuals based on genotype QC

775

DM_RET_VEIN_OCCLU

Control definitions

Control exclude DM_OPTHALMIC_COMORB

Control conditions not DIABETES_FG

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H34

Name in latin Aliae occlusiones vasculares retinae specificatae

NAME	DM_RET_VEIN_OCCLU
CONTROL_EXCLUDE	DM_OPTHALMIC_COMORB
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS	!DIABETES_FG
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS	DIABETES_FG
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H348
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H348
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Retinal vein occlusion (central or branch) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	775	337	438
Unadjusted prevalence (%)	0.21	0.16	0.26
Mean age at first event (years)	68.09	67.39	68.63

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.22 [1.78, 5.82]	1.1e-4	139
15 years	0.01	1.61 [0.87, 2.98]	1.3e-1	61
5 years	0.00	3.39 [1.77, 6.51]	2.4e-4	53
1 year	0.00	4.91 [2.40, 10.05]	1.3e-5	15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_RET_VEIN_OCCLU – Retinal vein occlusion (central or branch)
GWS hits:

Survival analyses between endpoints

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Plot

before Retinal vein occlusion (central or branch)
after Retinal vein occlusion (central or branch)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Retinal vein occlusion (central or branch)

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3