Disorders of orbit

H7_ORBIT

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H05, H06*
Cause of death: ICD-10 H05, H06*

2 out of 7 registries used, show all original rules.

1165

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Check minimum number of events None

1165

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Remove individuals based on genotype QC

1199

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H7_ORBIT

Control definitions

Control exclude H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of orbit based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1199 839 360
Unadjusted prevalence (%) 0.32 0.40 0.22
Mean age at first event (years) 50.64 50.21 51.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.23 [1.96, 5.32] 4.0e-6 89
15 years 0.01 1.81 [1.17, 2.79] 7.1e-3 34
5 years 0.01 4.70 [3.01, 7.32] 8.2e-12 28
1 year 0.00 10.42 [5.61, 19.37] 1.2e-13 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_ORBIT – Disorders of orbit
GWS hits: 2

Survival analyses between endpoints

Plot

before Disorders of orbit
after Disorders of orbit

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Drugs most likely to be purchased after Disorders of orbit

Endpoint not on priority list, no data to show.