Graves ophthalmopathy, strict

E4_GRAVES_OPHT_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H06.2*E05.9

Cause of death: ICD-10 H06.2*E05.9

2 out of 7 registries used, show all original rules.

582

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Check minimum number of events None

582

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Include endpoints None

582

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Remove individuals based on genotype QC

561

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E4_GRAVES_OPHT_STRICT

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF7

NAME	E4_GRAVES_OPHT_STRICT
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H062&E059
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H062&E059
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Graves ophthalmopathy, strict based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	561	454	107
Unadjusted prevalence (%)	0.15	0.22	0.06
Mean age at first event (years)	52.18	51.72	54.17

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.46 [0.09, 2.30]	3.5e-1	18
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GRAVES_OPHT_STRICT – Graves ophthalmopathy, strict
GWS hits:

Survival analyses between endpoints

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Plot

before Graves ophthalmopathy, strict
after Graves ophthalmopathy, strict

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Table

Loading survival analyses table

Drugs most likely to be purchased after Graves ophthalmopathy, strict

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Endpoint not on priority list, no data to show.