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Disorders of eyelid, lacrimal system and orbit

DOID EFO MESH SNOMED PheWeb

H7_LIDLACRIMALORBIT

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H00-H06
Cause of death: ICD-10 H00-H06

2 out of 7 registries used, show all original rules.

32823

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Check minimum number of events None

32823

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Include endpoints

33743

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Remove individuals based on genotype QC

32593

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H7_LIDLACRIMALORBIT

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 32593 21184 11409
Unadjusted prevalence (%) 8.64 10.05 6.86
Mean age at first event (years) 57.41 55.61 60.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.01 [1.77, 2.29] 3.4e-26 2682
15 years 0.01 1.21 [1.07, 1.37] 2.2e-3 1262
5 years 0.00 2.14 [1.92, 2.40] 5.1e-41 837
1 year 0.00 3.09 [2.62, 3.64] 4.5e-41 237

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_LIDLACRIMALORBIT – Disorders of eyelid, lacrimal system and orbit
GWS hits: 1

Survival analyses between endpoints

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Plot

before Disorders of eyelid, lacrimal system and orbit
after Disorders of eyelid, lacrimal system and orbit

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of eyelid, lacrimal system and orbit

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Endpoint not on priority list, no data to show.