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Diabetic maculopathy

H7_MACULOPATHYDIAB

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H36.01*
Cause of death: ICD-10 H36.01*

2 out of 7 registries used, show all original rules.

3675

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Check minimum number of events None

3675

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Include endpoints None

3675

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Remove individuals based on genotype QC

3572

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H7_MACULOPATHYDIAB

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3572 1477 2095
Unadjusted prevalence (%) 0.95 0.70 1.26
Mean age at first event (years) 52.71 51.11 53.83

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: H7_MACULOPATHYDIAB – Diabetic maculopathy
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Diabetic maculopathy

Endpoint not on priority list, no data to show.