Disorders of lacrimal system

H7_LACRIMALSYSTEM

lacrimal apparatus disease: A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus. [ NCIT:C26809 ]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H04
Cause of death: ICD-10 H04

2 out of 7 registries used, show all original rules.

13459

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Check minimum number of events None

13459

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Remove individuals based on genotype QC

13326

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H7_LACRIMALSYSTEM

Control definitions

Control exclude H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H00-H06
Name in latin Morbositates apparati lacrimalis

Similar endpoints

List of similar endpoints to Disorders of lacrimal system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 13326 9592 3734
Unadjusted prevalence (%) 3.53 4.55 2.25
Mean age at first event (years) 56.12 55.04 58.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.13 [1.71, 2.66] 2.0e-11 861
15 years 0.01 1.25 [1.02, 1.52] 2.9e-2 403
5 years 0.00 2.21 [1.82, 2.68] 5.8e-16 270
1 year 0.00 3.27 [2.50, 4.27] 3.3e-18 80

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_LACRIMALSYSTEM – Disorders of lacrimal system
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of lacrimal system
after Disorders of lacrimal system

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Drugs most likely to be purchased after Disorders of lacrimal system

Endpoint not on priority list, no data to show.