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Generalized epilepsy, strict definition

DOID EFO MESH SNOMED PheWeb

GE_STRICT

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not FE

385352

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

GE

697

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Remove individuals based on genotype QC

669

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GE_STRICT

Control definitions

Control exclude G6_EPLEPSY
Control conditions not FE

Extra metadata

First used in FinnGen datafreeze DF3

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 669 412 257
Unadjusted prevalence (%) 0.18 0.20 0.15
Mean age at first event (years) 30.53 28.83 33.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.38 [1.50, 7.60] 3.2e-3 59
15 years 0.02 2.45 [1.29, 4.67] 6.3e-3 27
5 years 0.00 3.95 [2.07, 7.52] 3.0e-5 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GE_STRICT – Generalized epilepsy, strict definition
GWS hits:

Survival analyses between endpoints

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Plot

before Generalized epilepsy, strict definition
after Generalized epilepsy, strict definition

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Drugs most likely to be purchased after Generalized epilepsy, strict definition

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Endpoint not on priority list, no data to show.