Diseases of the myoneural junction and muscle

G6_MYONEU

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G70-G73, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18
Cause of death: ICD-10 G70-G73, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18

2 out of 7 registries used, show all original rules.

3477

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Check minimum number of events None

3477

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Remove individuals based on genotype QC

3429

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G6_MYONEU

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Diseases of the myoneural junction and muscle based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 3429 1567 1862
Unadjusted prevalence (%) 0.91 0.74 1.12
Mean age at first event (years) 57.88 55.48 59.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.77 [4.20, 10.91] 4.2e-15 677
15 years 0.01 2.27 [1.57, 3.28] 1.5e-5 183
5 years 0.01 6.61 [4.96, 8.82] 7.7e-38 259
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MYONEU – Diseases of the myoneural junction and muscle
GWS hits: 11

Survival analyses between endpoints

Plot

before Diseases of the myoneural junction and muscle
after Diseases of the myoneural junction and muscle

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Drugs most likely to be purchased after Diseases of the myoneural junction and muscle

Endpoint not on priority list, no data to show.