Other and unspecified myopathies

G6_MYOPOTHUNS

myopathy: a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G72.8, G72.9
Hospital discharge: ICD-9 3594B|359[8-9]
Cause of death: ICD-10 G72.8, G72.9
Cause of death: ICD-9 3594B|359[8-9]

2 out of 7 registries used, show all original rules.

2385

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Check minimum number of events None

2385

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Include endpoints None

2385

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Remove individuals based on genotype QC

2313

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G6_MYOPOTHUNS

Control definitions

Control exclude G6_MYONEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2313 940 1373
Unadjusted prevalence (%) 0.61 0.45 0.83
Mean age at first event (years) 61.57 60.33 62.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 8.12 [5.66, 11.65] 5.7e-30 536
15 years 0.01 2.19 [1.51, 3.18] 3.5e-5 132
5 years 0.01 5.64 [3.57, 8.90] 1.1e-13 220
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MYOPOTHUNS – Other and unspecified myopathies
GWS hits: 2

Survival analyses between endpoints

Plot

before Other and unspecified myopathies
after Other and unspecified myopathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified myopathies

Endpoint not on priority list, no data to show.