Other and unspecified myopathies

DOID EFO MESH SNOMED PheWeb

G6_MYOPOTHUNS

myopathy: a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G72.8, G72.9

Hospital discharge: ICD-9 3594B|359[8-9]

Cause of death: ICD-10 G72.8, G72.9

Cause of death: ICD-9 3594B|359[8-9]

2 out of 7 registries used, show all original rules.

2385

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Check minimum number of events None

2385

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Include endpoints None

2385

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Remove individuals based on genotype QC

2313

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G6_MYOPOTHUNS

Control definitions

Control exclude G6_MYONEU

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	G6_MYOPOTHUNS
CONTROL_EXCLUDE	G6_MYONEU
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G72[8-9]
HD_ICD_9	3594B\|359[8-9]
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G72[8-9]
COD_ICD_9	3594B\|359[8-9]
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other and unspecified myopathies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2313	940	1373
Unadjusted prevalence (%)	0.61	0.45	0.83
Mean age at first event (years)	61.57	60.33	62.42

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.12	8.12 [5.66, 11.65]	5.7e-30	536
15 years	0.01	2.19 [1.51, 3.18]	3.5e-5	132
5 years	0.01	5.64 [3.57, 8.90]	1.1e-13	220
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MYOPOTHUNS – Other and unspecified myopathies
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other and unspecified myopathies
after Other and unspecified myopathies

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Table

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Drugs most likely to be purchased after Other and unspecified myopathies

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Endpoint not on priority list, no data to show.