Felty syndrome

FELTY

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05.0
Hospital discharge: ICD-9 7141
Hospital discharge: ICD-8 71210
Cause of death: ICD-10 M05.0
Cause of death: ICD-9 7141
Cause of death: ICD-8 71210

2 out of 7 registries used, show all original rules.

154

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Check minimum number of events None

154

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Include endpoints None

154

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Remove individuals based on genotype QC

151

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FELTY

Control definitions

Control exclude RHEUMA_SEROPOS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05
Name in latin Syndroma Felty

Summary Statistics

Key figures

All Female Male
Number of individuals 151 111 40
Unadjusted prevalence (%) 0.04 0.05 0.02
Mean age at first event (years) 58.78 58.66 59.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FELTY – Felty syndrome
GWS hits:

Survival analyses between endpoints

Plot

before Felty syndrome
after Felty syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Felty syndrome

Endpoint not on priority list, no data to show.