Felty syndrome


Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M05.0
Hospital discharge: ICD-9 7141
Hospital discharge: ICD-8 71210
Cause of death: ICD-10 M05.0
Cause of death: ICD-9 7141
Cause of death: ICD-8 71210

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude RHEUMA_SEROPOS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05
Name in latin Syndroma Felty

Summary Statistics

Key figures

All Female Male
Number of individuals 151 111 40
Unadjusted prevalence (%) 0.04 0.05 0.02
Mean age at first event (years) 58.78 58.66 59.12


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: FELTY – Felty syndrome
GWS hits:

Survival analyses between endpoints


before Felty syndrome
after Felty syndrome

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Drugs most likely to be purchased after Felty syndrome

Endpoint not on priority list, no data to show.