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Hyperprolactinaemia

DOID EFO MESH SNOMED PheWeb

E4_HYPERPRO

hyperprolactinemia: An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E22.1#
Hospital discharge: ICD-9 2531A
Cause of death: ICD-10 E22.1#
Cause of death: ICD-9 2531A

2 out of 7 registries used, show all original rules.

1053

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Check minimum number of events None

1053

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Include endpoints None

1053

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Remove individuals based on genotype QC

1014

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E4_HYPERPRO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E22
Name in latin Hyperprolactinaemia

Summary Statistics

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Key figures

All Female Male
Number of individuals 1014 847 167
Unadjusted prevalence (%) 0.27 0.40 0.10
Mean age at first event (years) 37.91 35.61 49.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.14 [0.80, 5.73] 1.3e-1 26
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERPRO – Hyperprolactinaemia
GWS hits:

Survival analyses between endpoints

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Plot

before Hyperprolactinaemia
after Hyperprolactinaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hyperprolactinaemia

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Endpoint not on priority list, no data to show.