Hyperprolactinaemia

E4_HYPERPRO

hyperprolactinemia: An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E22.1#
Hospital discharge: ICD-9 2531A
Cause of death: ICD-10 E22.1#
Cause of death: ICD-9 2531A

2 out of 7 registries used, show all original rules.

1053

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Check minimum number of events None

1053

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Include endpoints None

1053

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Remove individuals based on genotype QC

1014

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E4_HYPERPRO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E22
Name in latin Hyperprolactinaemia

Summary Statistics

Key figures

All Female Male
Number of individuals 1014 847 167
Unadjusted prevalence (%) 0.27 0.40 0.10
Mean age at first event (years) 37.91 35.61 49.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.14 [0.80, 5.73] 1.3e-1 26
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_HYPERPRO – Hyperprolactinaemia
GWS hits:

Survival analyses between endpoints

Plot

before Hyperprolactinaemia
after Hyperprolactinaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hyperprolactinaemia

Endpoint not on priority list, no data to show.