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Hyperfunction of pituitary gland, other and/or unspecified

DOID EFO MESH SNOMED PheWeb

E4_HYPERPITNAS

hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E22.9
Hospital discharge: ICD-9 2531X
Hospital discharge: ICD-8 25301
Cause of death: ICD-10 E22.9
Cause of death: ICD-9 2531X
Cause of death: ICD-8 25301

2 out of 7 registries used, show all original rules.

50

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Check minimum number of events None

50

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Include endpoints None

50

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Remove individuals based on genotype QC

50

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E4_HYPERPITNAS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 E22
Name in latin Hyperfunctio hypophysis non specificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 50 32 18
Unadjusted prevalence (%) 0.01 0.02 0.01
Mean age at first event (years) 48.75 44.22 56.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERPITNAS – Hyperfunction of pituitary gland, other and/or unspecified
GWS hits:

Survival analyses between endpoints

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Plot

before Hyperfunction of pituitary gland, other and/or unspecified
after Hyperfunction of pituitary gland, other and/or unspecified

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Drugs most likely to be purchased after Hyperfunction of pituitary gland, other and/or unspecified

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Endpoint not on priority list, no data to show.