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Graves disease, strict definition

PheWeb

E4_GRAVES_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

GRAVES_COND
and not AMIODARONE

6318

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

2939

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Remove individuals based on genotype QC

2836

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E4_GRAVES_STRICT

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 2836 2396 440
Unadjusted prevalence (%) 0.75 1.14 0.26
Mean age at first event (years) 49.03 48.36 52.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.97 [1.17, 3.32] 1.1e-2 73
15 years 0.01 1.11 [0.66, 1.86] 6.9e-1 35
5 years 0.00 1.71 [1.00, 2.92] 4.9e-2 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_GRAVES_STRICT – Graves disease, strict definition
GWS hits: 11

Survival analyses between endpoints

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Plot

before Graves disease, strict definition
after Graves disease, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Graves disease, strict definition

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Endpoint not on priority list, no data to show.