Endocrine disorders, other/unspecified

DOID EFO MESH SNOMED PheWeb

E4_ENDODISNAS

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E34.8, E34.9

Hospital discharge: ICD-9 2592

Hospital discharge: ICD-8 2589

Cause of death: ICD-10 E34.8, E34.9

Cause of death: ICD-9 2592

Cause of death: ICD-8 2589

2 out of 7 registries used, show all original rules.

601

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Check minimum number of events None

601

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Include endpoints None

601

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Remove individuals based on genotype QC

588

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E4_ENDODISNAS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

NAME	E4_ENDODISNAS
CONTROL_EXCLUDE	E4_ENDOGLAND
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E34[8-9]
HD_ICD_9	2592
HD_ICD_8	2589
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E34[8-9]
COD_ICD_9	2592
COD_ICD_8	2589
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Endocrine disorders, other/unspecified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	588	393	195
Unadjusted prevalence (%)	0.16	0.19	0.12
Mean age at first event (years)	43.04	41.00	47.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.68 [0.83, 3.40]	1.5e-1	44
15 years	0.01	1.00 [0.46, 2.18]	1.0e+0	23
5 years	0.00	1.79 [0.78, 4.13]	1.7e-1	11
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ENDODISNAS – Endocrine disorders, other/unspecified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Endocrine disorders, other/unspecified
after Endocrine disorders, other/unspecified

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Table

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Drugs most likely to be purchased after Endocrine disorders, other/unspecified

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Endpoint not on priority list, no data to show.