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Certain disorders involving the immune mechanism

DOID EFO MESH SNOMED PheWeb

D3_IMMUNEMECHANISM

immune system disease: A disorder resulting from an abnormality in the immune system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

6231

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Remove individuals based on genotype QC

6022

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D3_IMMUNEMECHANISM

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Certain disorders involving the immune mechanism based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 6022 3335 2687
Unadjusted prevalence (%) 1.60 1.58 1.62
Mean age at first event (years) 47.30 46.93 47.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.00 [1.46, 2.73] 1.8e-5 537
15 years 0.01 1.25 [0.92, 1.68] 1.5e-1 202
5 years 0.00 2.98 [2.29, 3.88] 3.8e-16 127
1 year 0.00 9.00 [6.65, 12.17] 4.9e-46 71

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_IMMUNEMECHANISM – Certain disorders involving the immune mechanism
GWS hits: 8

Survival analyses between endpoints

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Plot

before Certain disorders involving the immune mechanism
after Certain disorders involving the immune mechanism

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Drugs most likely to be purchased after Certain disorders involving the immune mechanism

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Endpoint not on priority list, no data to show.