Immunodeficiency with predominantly antibody defects

D3_IMMUDEFANTIBODY

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D80
Cause of death: ICD-10 D80

2 out of 7 registries used, show all original rules.

722

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Check minimum number of events None

722

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Remove individuals based on genotype QC

711

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D3_IMMUDEFANTIBODY

Control definitions

Control exclude D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D80-D89
Name in latin Deficientia immunalis praecipue cum vitiis anticorporum

Similar endpoints

List of similar endpoints to Immunodeficiency with predominantly antibody defects based on the number of shared cases.

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Summary Statistics

Key figures

All Female Male
Number of individuals 711 469 242
Unadjusted prevalence (%) 0.19 0.22 0.15
Mean age at first event (years) 46.24 45.76 47.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.26 18.79 [9.55, 36.95] 1.9e-17 62
15 years 0.05 7.10 [3.55, 14.19] 2.9e-8 22
5 years 0.02 17.37 [9.78, 30.87] 2.1e-22 25
1 year 0.01 40.15 [19.71, 81.80] 2.7e-24 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_IMMUDEFANTIBODY – Immunodeficiency with predominantly antibody defects
GWS hits:

Survival analyses between endpoints

Plot

before Immunodeficiency with predominantly antibody defects
after Immunodeficiency with predominantly antibody defects

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Drugs most likely to be purchased after Immunodeficiency with predominantly antibody defects

Endpoint not on priority list, no data to show.