Immunodeficiencies

D3_IMMUDEF

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

1350

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D3_IMMUDEF

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Immunodeficiencies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1350 861 489
Unadjusted prevalence (%) 0.36 0.41 0.29
Mean age at first event (years) 47.80 46.20 50.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.19 [5.02, 10.30] 6.2e-27 163
15 years 0.02 3.28 [2.31, 4.65] 2.9e-11 57
5 years 0.01 8.04 [5.64, 11.44] 6.4e-31 52
1 year 0.01 25.90 [17.25, 38.87] 1.4e-55 34

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_IMMUDEF – Immunodeficiencies
GWS hits:

Survival analyses between endpoints

Plot

before Immunodeficiencies
after Immunodeficiencies

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Drugs most likely to be purchased after Immunodeficiencies

Endpoint not on priority list, no data to show.