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Haemolytic anaemias

DOID EFO MESH SNOMED PheWeb

D3_HAEMOLYTICANAEMIA

hemolytic anemia: Hemolytic anemia that is not mediated by immune mechanisms.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

942

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Remove individuals based on genotype QC

838

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D3_HAEMOLYTICANAEMIA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Haemolytic anaemias based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 838 418 420
Unadjusted prevalence (%) 0.22 0.20 0.25
Mean age at first event (years) 52.74 48.88 56.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.28 [2.19, 8.37] 2.1e-5 159
15 years 0.01 1.37 [0.64, 2.95] 4.2e-1 43
5 years 0.00 4.14 [1.90, 9.00] 3.4e-4 57
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_HAEMOLYTICANAEMIA – Haemolytic anaemias
GWS hits:

Survival analyses between endpoints

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Plot

before Haemolytic anaemias
after Haemolytic anaemias

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Drugs most likely to be purchased after Haemolytic anaemias

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Endpoint not on priority list, no data to show.