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Thalassaemia

DOID EFO MESH SNOMED PheWeb

D3_THALASSAEMIA

Thalassemia: An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D56
Cause of death: ICD-10 D56

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints

105

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Remove individuals based on genotype QC

43

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D3_THALASSAEMIA

Control definitions

Control exclude D3_HAEMOLYTICANAEMIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D55-D59
Name in latin Thalassaemia

Similar endpoints

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List of similar endpoints to Thalassaemia based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 43 22 21
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 50.72 51.51 49.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_THALASSAEMIA – Thalassaemia
GWS hits:

Survival analyses between endpoints

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Plot

before Thalassaemia
after Thalassaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Thalassaemia

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Endpoint not on priority list, no data to show.