Defects in the complement system

D3_COMPLEMENTDEF

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D84.1
Hospital discharge: ICD-9 2798B
Cause of death: ICD-10 D84.1
Cause of death: ICD-9 2798B

2 out of 7 registries used, show all original rules.

182

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Check minimum number of events None

182

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Include endpoints None

182

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Remove individuals based on genotype QC

171

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D3_COMPLEMENTDEF

Control definitions

Control exclude D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D84
Name in latin Deficientia systematis complementi

Summary Statistics

Key figures

All Female Male
Number of individuals 171 127 44
Unadjusted prevalence (%) 0.05 0.06 0.03
Mean age at first event (years) 42.16 42.24 41.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D3_COMPLEMENTDEF – Defects in the complement system
GWS hits: 1

Survival analyses between endpoints

Plot

before Defects in the complement system
after Defects in the complement system

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Defects in the complement system

Endpoint not on priority list, no data to show.