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Cirrhosis of liver, NAS

DOID EFO MESH SNOMED PheWeb

CHIRHEP_NAS

non-alcoholic fatty liver disease: A term referring to fatty replacement of the hepatic parenchyma which is not related to alcohol use.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K74.6
Cause of death: ICD-10 K74.6

2 out of 7 registries used, show all original rules.

1174

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Check minimum number of events None

1174

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Include endpoints None

1174

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Remove individuals based on genotype QC

1142

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CHIRHEP_NAS

Control definitions

Control exclude CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis hepatis alia sive non specificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 1142 458 684
Unadjusted prevalence (%) 0.30 0.22 0.41
Mean age at first event (years) 63.86 61.98 65.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHIRHEP_NAS – Cirrhosis of liver, NAS
GWS hits: 5

Survival analyses between endpoints

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Plot

before Cirrhosis of liver, NAS
after Cirrhosis of liver, NAS

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cirrhosis of liver, NAS

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Endpoint not on priority list, no data to show.