Biliary cirrhosis, secondary

CHIRBIL_SEC

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K74.4
Cause of death: ICD-10 K74.4

2 out of 7 registries used, show all original rules.

22

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Check minimum number of events None

22

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Include endpoints None

22

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Remove individuals based on genotype QC

22

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CHIRBIL_SEC

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis biliaris secundaria

Summary Statistics

Key figures

All Female Male
Number of individuals 22 16 6
Unadjusted prevalence (%) 0.01 0.01 0.00
Mean age at first event (years) 52.75 54.02 49.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHIRBIL_SEC – Biliary cirrhosis, secondary
GWS hits:

Survival analyses between endpoints

Plot

before Biliary cirrhosis, secondary
after Biliary cirrhosis, secondary

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Biliary cirrhosis, secondary

Endpoint not on priority list, no data to show.