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Charcot foot

PheWeb

CHARCOT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6
Cause of death: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6

2 out of 7 registries used, show all original rules.

486

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Check minimum number of events None

486

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Include endpoints None

486

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Remove individuals based on genotype QC

473

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CHARCOT

Control definitions

Control exclude DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 473 182 291
Unadjusted prevalence (%) 0.13 0.09 0.18
Mean age at first event (years) 55.84 53.69 57.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 11.46 [7.17, 18.32] 2.1e-24 92
15 years 0.04 6.12 [3.72, 10.08] 1.1e-12 47
5 years 0.01 9.78 [5.26, 18.15] 5.2e-13 33
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHARCOT – Charcot foot
GWS hits:

Survival analyses between endpoints

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Plot

before Charcot foot
after Charcot foot

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Charcot foot

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Endpoint not on priority list, no data to show.