Charcot foot

CHARCOT

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6
Cause of death: ICD-10 M14.6*A52.1, M14.6*E10.6, M14.6*E11.6

2 out of 7 registries used, show all original rules.

486

diagram downward connector

Check minimum number of events None

486

diagram downward connector

Include endpoints None

486

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

473

diagram downward connector
CHARCOT

Control definitions

Control exclude DM_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 473 182 291
Unadjusted prevalence (%) 0.13 0.09 0.18
Mean age at first event (years) 55.84 53.69 57.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 11.46 [7.17, 18.32] 2.1e-24 92
15 years 0.04 6.12 [3.72, 10.08] 1.1e-12 47
5 years 0.01 9.78 [5.26, 18.15] 5.2e-13 33
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHARCOT – Charcot foot
GWS hits:

Survival analyses between endpoints

Plot

before Charcot foot
after Charcot foot

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Charcot foot

Endpoint not on priority list, no data to show.