Asthma-related pneumonia

ASTHMA_PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

J10_ASTHMA

43630

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

12044

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ASTHMA_PNEUMONIA

Control definitions

Control exclude ASTHMA_INFECTIONS
Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 12044 6192 5852
Unadjusted prevalence (%) 3.19 2.94 3.52
Mean age at first event (years) 54.19 50.93 57.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.54 [3.79, 5.43] 1.0e-60 2832
15 years 0.01 1.96 [1.67, 2.29] 6.7e-17 915
5 years 0.01 4.38 [3.87, 4.95] <1e-100 839
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ASTHMA_PNEUMONIA – Asthma-related pneumonia
GWS hits: 8

Survival analyses between endpoints

Plot

before Asthma-related pneumonia
after Asthma-related pneumonia

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Drugs most likely to be purchased after Asthma-related pneumonia

Endpoint not on priority list, no data to show.