Ulcerative rectosigmoiditis

ULCERRECT

ulcerative proctosigmoiditis: Inflammation of the rectum and the distal portion of the colon.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51.3
Cause of death: ICD-10 K51.3

2 out of 7 registries used, show all original rules.

2557

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Check minimum number of events None

2557

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Include endpoints None

2557

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Remove individuals based on genotype QC

2487

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ULCERRECT

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Rectosigmoiditis ulcerosa [chronica]

Summary Statistics

Key figures

All Female Male
Number of individuals 2487 1303 1184
Unadjusted prevalence (%) 0.66 0.62 0.71
Mean age at first event (years) 46.12 43.02 49.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.88 [0.31, 2.50] 8.1e-1 137
15 years 0.01 0.79 [0.34, 1.83] 5.8e-1 64
5 years 0.00 1.58 [0.75, 3.30] 2.3e-1 30
1 year 0.00 3.44 [1.54, 7.70] 2.7e-3 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ULCERRECT – Ulcerative rectosigmoiditis
GWS hits: 13

Survival analyses between endpoints

Plot

before Ulcerative rectosigmoiditis
after Ulcerative rectosigmoiditis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative rectosigmoiditis

Endpoint not on priority list, no data to show.