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Noninfective enteritis and colitis

DOID EFO MESH SNOMED PheWeb

K11_ENERCOLNONINF

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50-K52
Cause of death: ICD-10 K50-K52

2 out of 7 registries used, show all original rules.

16045

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Check minimum number of events None

16045

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Include endpoints

17915

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Remove individuals based on genotype QC

17350

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K11_ENERCOLNONINF

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 17350 9630 7720
Unadjusted prevalence (%) 4.60 4.57 4.64
Mean age at first event (years) 44.79 43.14 46.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.30 [1.97, 2.69] 3.1e-25 1782
15 years 0.01 1.24 [1.06, 1.44] 5.5e-3 670
5 years 0.00 2.59 [2.26, 2.96] 2.8e-43 457
1 year 0.00 9.08 [7.76, 10.63] <1e-100 323

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ENERCOLNONINF – Noninfective enteritis and colitis
GWS hits: 29

Survival analyses between endpoints

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Plot

before Noninfective enteritis and colitis
after Noninfective enteritis and colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Noninfective enteritis and colitis

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Endpoint not on priority list, no data to show.