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Other ulcerative colitis

DOID EFO MESH SNOMED PheWeb

ULCEROTH

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51.8
Cause of death: ICD-10 K51.8

2 out of 7 registries used, show all original rules.

1739

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Check minimum number of events None

1739

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Include endpoints None

1739

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Remove individuals based on genotype QC

1692

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ULCEROTH

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K51
Name in latin Alia colitis ulcerosa specificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 1692 889 803
Unadjusted prevalence (%) 0.45 0.42 0.48
Mean age at first event (years) 44.96 42.76 47.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.68 [0.67, 4.26] 2.7e-1 105
15 years 0.01 1.33 [0.64, 2.76] 4.5e-1 48
5 years 0.00 2.07 [1.05, 4.08] 3.7e-2 20
1 year 0.00 10.40 [5.28, 20.51] 1.4e-11 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ULCEROTH – Other ulcerative colitis
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other ulcerative colitis
after Other ulcerative colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other ulcerative colitis

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Endpoint not on priority list, no data to show.