Type 1 diabetes, wide definition, subgroup 2

T1D_WIDE2

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not PANCREATITIS
and not INSULIN_INTER_AND_LONG
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST

871

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

522

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Remove individuals based on genotype QC

500

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T1D_WIDE2

Control definitions

Control exclude DIABETES_FG
Control conditions not PANCREATITIS
and not INSULIN_INTER_AND_LONG
and not KELA_DIAB_INSUL
and not INSULIN_SHORTFAST

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 500 207 293
Unadjusted prevalence (%) 0.13 0.10 0.18
Mean age at first event (years) 45.55 44.08 46.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: T1D_WIDE2 – Type 1 diabetes, wide definition, subgroup 2
GWS hits: 1

Survival analyses between endpoints

Plot

before Type 1 diabetes, wide definition, subgroup 2
after Type 1 diabetes, wide definition, subgroup 2

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Drugs most likely to be purchased after Type 1 diabetes, wide definition, subgroup 2

Endpoint not on priority list, no data to show.