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Type1 diabetes, definitions combined, early onset

PheWeb

T1D_EARLY

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Pre-conditions EVENT_AGE < 20

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

T1D

2833

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Remove individuals based on genotype QC

2770

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T1D_EARLY

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 2770 1441 1329
Unadjusted prevalence (%) 0.73 0.68 0.80
Mean age at first event (years) 9.66 9.63 9.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 8.51 [4.32, 16.75] 5.8e-10 68
15 years 0.07 11.19 [5.55, 22.57] 1.5e-11 38
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_EARLY – Type1 diabetes, definitions combined, early onset
GWS hits: 22

Survival analyses between endpoints

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Plot

before Type1 diabetes, definitions combined, early onset
after Type1 diabetes, definitions combined, early onset

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Drugs most likely to be purchased after Type1 diabetes, definitions combined, early onset

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Endpoint not on priority list, no data to show.