≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

SLE (Finngen)

DOID MESH PheWeb

SLE_FG

No definition available.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

1057

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1023

diagram downward connector
SLE_FG

Control definitions

Control exclude AUTOIMMUNE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 1023 849 174
Unadjusted prevalence (%) 0.27 0.40 0.10
Mean age at first event (years) 45.82 44.68 51.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.04 [1.51, 10.87] 5.6e-3 94
15 years 0.02 2.84 [1.36, 5.91] 5.2e-3 39
5 years 0.01 5.23 [2.88, 9.49] 5.1e-8 22
1 year 0.00 15.74 [8.08, 30.67] 5.4e-16 13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: SLE_FG – SLE (Finngen)
GWS hits: 6

Survival analyses between endpoints

↥

Plot

before SLE (Finngen)
after SLE (Finngen)

loading spinner Loading survival analyses plot