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Other (seronegative) rheumatoid arthritis, wide

DOID EFO MESH SNOMED PheWeb

RHEUMA_OTHER_WIDE

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M06
Hospital discharge: ICD-9 7140B|7148|7142
Cause of death: ICD-10 M06
Cause of death: ICD-9 7140B|7148|7142

2 out of 7 registries used, show all original rules.

6305

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Check minimum number of events None

6305

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Include endpoints None

6305

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Remove individuals based on genotype QC

6153

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RHEUMA_OTHER_WIDE

Control definitions

Control exclude STILL_ADULT

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14
Name in latin Alia arthritis rheumatoides

Summary Statistics

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Key figures

All Female Male
Number of individuals 6153 4190 1963
Unadjusted prevalence (%) 1.63 1.99 1.18
Mean age at first event (years) 55.01 53.02 59.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.41 [1.78, 3.26] 1.4e-8 786
15 years 0.01 1.55 [1.23, 1.96] 2.2e-4 334
5 years 0.00 3.03 [2.49, 3.68] 7.3e-29 220
1 year 0.00 7.68 [6.04, 9.76] 3.0e-62 110

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_OTHER_WIDE – Other (seronegative) rheumatoid arthritis, wide
GWS hits: 4

Survival analyses between endpoints

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Plot

before Other (seronegative) rheumatoid arthritis, wide
after Other (seronegative) rheumatoid arthritis, wide

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other (seronegative) rheumatoid arthritis, wide

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Endpoint not on priority list, no data to show.