Left ventricular outflow tract obstruction, narrow definition

Q17_LVOTO_NARROW

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
Hospital discharge: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Hospital discharge: excluded ICD-9 758|7595|75683
Cause of death: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
Cause of death: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Cause of death: excluded ICD-9 758|7595|75683

2 out of 7 registries used, show all original rules.

1298

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Check minimum number of events None

1298

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Include endpoints None

1298

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Remove individuals based on genotype QC

1243

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Q17_LVOTO_NARROW

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 1243 456 787
Unadjusted prevalence (%) 0.33 0.22 0.47
Mean age at first event (years) 41.70 37.66 44.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.93 [0.83, 4.50] 1.3e-1 61
15 years 0.01 1.03 [0.45, 2.32] 9.5e-1 22
5 years 0.00 1.56 [0.68, 3.59] 3.0e-1 15
1 year 0.00 6.32 [2.74, 14.55] 1.5e-5 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: Q17_LVOTO_NARROW – Left ventricular outflow tract obstruction, narrow definition
GWS hits:

Survival analyses between endpoints

Plot

before Left ventricular outflow tract obstruction, narrow definition
after Left ventricular outflow tract obstruction, narrow definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Left ventricular outflow tract obstruction, narrow definition

Endpoint not on priority list, no data to show.