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Primary gonarthrosis, bilateral

MESH PheWeb

PRIM_KNEEARTHROSIS

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M17.0
Cause of death: ICD-10 M17.0

2 out of 7 registries used, show all original rules.

17480

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Check minimum number of events None

17480

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Include endpoints None

17480

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Remove individuals based on genotype QC

17009

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PRIM_KNEEARTHROSIS

Control definitions

Control exclude KNEE_ARTHROSIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M17
Name in latin Gonarthrosis primaria bilateralis

Summary Statistics

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Key figures

All Female Male
Number of individuals 17009 10441 6568
Unadjusted prevalence (%) 4.51 4.95 3.95
Mean age at first event (years) 64.18 63.82 64.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.45 [1.18, 1.78] 3.7e-4 1611
15 years 0.01 1.08 [0.91, 1.28] 3.7e-1 903
5 years 0.00 1.44 [1.22, 1.69] 8.9e-6 386
1 year 0.00 1.64 [1.27, 2.12] 1.3e-4 82

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: PRIM_KNEEARTHROSIS – Primary gonarthrosis, bilateral
GWS hits: 25

Survival analyses between endpoints

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Plot

before Primary gonarthrosis, bilateral
after Primary gonarthrosis, bilateral

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary gonarthrosis, bilateral

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Endpoint not on priority list, no data to show.