≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Pre-eclampsia

DOID EFO MESH SNOMED PheWeb

O15_PREECLAMPS

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

219462

diagram downward connector

Check conditions None

219462

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O14
Hospital discharge: ICD-9 642[4-5]
Hospital discharge: ICD-8 6370[349]
Cause of death: ICD-10 O14
Cause of death: ICD-9 642[4-5]
Cause of death: ICD-8 6370[349]

2 out of 7 registries used, show all original rules.

6867

diagram downward connector

Check minimum number of events None

6867

diagram downward connector

Include endpoints None

6867

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

6663

diagram downward connector
O15_PREECLAMPS

Control definitions

Control exclude O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O10-O16
Name in latin Hypertensio gestationalis cum proteinuria significanti

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 6663 6663 -
Unadjusted prevalence (%) 1.77 3.16 -
Mean age at first event (years) 29.07 29.07 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.49 [0.35, 0.69] 3.7e-5 112
15 years 0.00 0.29 [0.19, 0.46] 1.4e-7 29
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: O15_PREECLAMPS – Pre-eclampsia
GWS hits: 2

Survival analyses between endpoints

↥

Plot

before Pre-eclampsia
after Pre-eclampsia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Pre-eclampsia

↥

Endpoint not on priority list, no data to show.