Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

O15_ICP_WIDE_EXMORE

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule

Sex only females

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O26.6
Hospital discharge: ICD-9 6467
Hospital discharge: ICD-8 6390
Cause of death: ICD-10 O26.6
Cause of death: ICD-9 6467
Cause of death: ICD-8 6390

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

2503

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O15_ICP_WIDE_EXMORE

Control definitions

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O26
Name in latin Morbositates hepatis in graviditate, intra labores et/sive in puerperio

Similar endpoints

List of similar endpoints to Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 2503 2503 -
Unadjusted prevalence (%) 0.66 1.19 -
Mean age at first event (years) 29.98 29.98 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.49 [0.23, 1.01] 5.3e-2 32
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_ICP_WIDE_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)
GWS hits: 24

Survival analyses between endpoints

Plot

before Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)
after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

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Drugs most likely to be purchased after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

Endpoint not on priority list, no data to show.