≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

PheWeb

O15_ICP_WIDE_EXMORE

No definition available.

Endpoint definition

↥
FinnGen phenotype data

individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

diagram downward connector

Check conditions None

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O26.6
Hospital discharge: ICD-9 6467
Hospital discharge: ICD-8 6390
Cause of death: ICD-10 O26.6
Cause of death: ICD-9 6467
Cause of death: ICD-8 6390

2 out of 7 registries used, show all original rules.

-

diagram downward connector

Check minimum number of events None

-

diagram downward connector

Include endpoints None

-

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

2503

diagram downward connector
O15_ICP_WIDE_EXMORE

Control definitions

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O26
Name in latin Morbositates hepatis in graviditate, intra labores et/sive in puerperio

Similar endpoints

↥

List of similar endpoints to Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2503 2503 -
Unadjusted prevalence (%) 0.66 1.19 -
Mean age at first event (years) 29.98 29.98 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.49 [0.23, 1.01] 5.3e-2 32
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: O15_ICP_WIDE_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)
GWS hits: 24

Survival analyses between endpoints

↥

Plot

before Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)
after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8 (more control exclusions)

↥

Endpoint not on priority list, no data to show.