Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions)

O15_ICP_EXMORE

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule

Sex only females

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O26.6
Hospital discharge: ICD-9 6467
Cause of death: ICD-10 O26.6
Cause of death: ICD-9 6467

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

2003

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O15_ICP_EXMORE

Control definitions

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O26
Name in latin Morbositates hepatis in graviditate, intra labores et/sive in puerperio

Similar endpoints

List of similar endpoints to Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 2003 2003 -
Unadjusted prevalence (%) 0.53 0.95 -
Mean age at first event (years) 30.65 30.65 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.68 [0.31, 1.48] 3.3e-1 14
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: O15_ICP_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions)
GWS hits: 19

Survival analyses between endpoints

Plot

before Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions)
after Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions)

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Drugs most likely to be purchased after Intrahepatic Cholestasis of Pregnancy (ICP)  (more control exclusions)

Endpoint not on priority list, no data to show.