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Gestational [pregnancy-induced] hypertension

DOID EFO MESH SNOMED PheWeb

O15_GESTAT_HYPERT

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O13
Hospital discharge: ICD-9 6423
Hospital discharge: ICD-8 63701
Cause of death: ICD-10 O13
Cause of death: ICD-9 6423
Cause of death: ICD-8 63701

2 out of 7 registries used, show all original rules.

8723

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Check minimum number of events None

8723

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Include endpoints None

8723

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Remove individuals based on genotype QC

8502

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O15_GESTAT_HYPERT

Control definitions

Control exclude O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O10-O16
Name in latin Hypertensio gestationalis sine proteinuria significanti

Summary Statistics

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Key figures

All Female Male
Number of individuals 8502 8502 -
Unadjusted prevalence (%) 2.25 4.03 -
Mean age at first event (years) 30.06 30.06 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.93 [0.66, 1.30] 6.5e-1 157
15 years 0.01 0.70 [0.47, 1.03] 7.3e-2 53
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension
GWS hits: 10

Survival analyses between endpoints

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Plot

before Gestational [pregnancy-induced] hypertension
after Gestational [pregnancy-induced] hypertension

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gestational [pregnancy-induced] hypertension

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Endpoint not on priority list, no data to show.