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Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

DOID EFO MESH SNOMED PheWeb

O15_EXIST_HYPERT_COMPLIC

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O10
Hospital discharge: ICD-9 6420
Cause of death: ICD-10 O10
Cause of death: ICD-9 6420

2 out of 7 registries used, show all original rules.

2274

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Check minimum number of events None

2274

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Include endpoints None

2274

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Remove individuals based on genotype QC

2223

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O15_EXIST_HYPERT_COMPLIC

Control definitions

Control exclude O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Summary Statistics

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Key figures

All Female Male
Number of individuals 2223 2223 -
Unadjusted prevalence (%) 0.59 1.05 -
Mean age at first event (years) 32.92 32.92 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.25 [0.66, 2.37] 4.9e-1 20
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
GWS hits: 3

Survival analyses between endpoints

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Plot

before Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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Drugs most likely to be purchased after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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Endpoint not on priority list, no data to show.