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Renal failure

DOID EFO MESH SNOMED PheWeb

N14_RENFAIL

kidney failure: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

14579

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Remove individuals based on genotype QC

14100

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N14_RENFAIL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 14100 4802 9298
Unadjusted prevalence (%) 3.74 2.28 5.59
Mean age at first event (years) 67.55 65.80 68.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 10.93 [9.02, 13.25] <1e-100 4571
15 years 0.02 2.54 [2.11, 3.06] 8.4e-23 811
5 years 0.01 8.03 [7.06, 9.13] <1e-100 1530
1 year 0.01 37.53 [33.47, 42.07] <1e-100 2165

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_RENFAIL – Renal failure
GWS hits: 3

Survival analyses between endpoints

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Plot

before Renal failure
after Renal failure

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Renal failure

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Endpoint not on priority list, no data to show.